Clinical pharmacokinetics turned into usable dosing — bioavailability, Vd, clearance and half-life, the loading and maintenance dose formulas, elimination kinetics and steady state.
Safe prescribing in pregnancy, paediatrics, the elderly, and renal or hepatic impairment — the teratogen list and the dose-adjustment rules examiners love.
Every interaction is either pharmacokinetic (changes the level) or pharmacodynamic (changes the effect) — with the enzyme inducers, inhibitors and high-risk drugs to know.
When to monitor drug levels, how to sample at steady state, and the target ranges for digoxin, lithium, phenytoin, aminoglycosides and the other narrow-index drugs.
How inherited variation shapes drug response — the metaboliser spectrum, the high-yield gene-drug pairings, and HLA associations.
Bioavailability and bioequivalence made simple — Cmax, Tmax and AUC, the crossover study design, the 90% CI 80–125% rule, biowaivers and the BCS.
Pharmacovigilance explained — definition, methods, ADR reporting and the Pharmacovigilance Programme of India (PvPI): IPC Ghaziabad, AMCs, VigiFlow to WHO VigiBase.
The WHO Guide to Good Prescribing in one method — the P-drug concept, the six-step process of rational treatment, and India’s NLEM 2022.
